There are important differences (during rising and falling blood alcohol levels) in the reaction time and accuracy of performance over the duration of exposure to elevated blood alcohol levels.
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Alcohol Produces Differential Effects on Executive Cognitive Function on the Rising and Falling Limbs of the Blood Alcohol Curve.
Reaction time of executive cognitive function is impaired during the rising but not the falling limb of the blood alcohol curve, while accuracy of executive cognitive function is impaired during both the rising and falling limbs. On average, testing during the rising limb of the blood alcohol concentration (BAC) was at about 70 minutes and the falling BAC at about 110 minutes after alcohol injection with a BAC of 0.08 - 0.09 gm/100ml at each time. (Data from 4 studies reviewed in Schweizer TA and Vogel-Sprott M, Experimental and Clinical Psychopharmacology, 16:240, 2008)
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CURRENT LESSON OBJECTIVES
- What constitutes 1 drink?
- How do the number of drinks affect blood alcohol levels and behavior?
- What is the difference in blood alcohol per drink in men and women?
- What are the factors that alter the relationship between drinks ingested and BAL?
- Describe the metabolism of ethyl, methyl and isopropyl alcohol.
- What is the most important genetic factor that alters alcohol metabolism and dependence?
- How does acute tolerance change the behavioral effects of ascending and descending BAL?
- How does subjective elation and intoxication relate to rising and falling BAL?
- How does alcohol induced stimulation and sedation relate to binge drinking?
- What are the motor and cognitive impairments along the ascending and falling BAL curve?
- What are the persistent effects of alcohol after BAL reaches 0?
- Describe chronic tolerance to alcohol effects.
- Summary
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