Social and family factors are involved in the amount of alcohol consumed in adolescence but genetic factors become more important in early adulthood.Most adolescents are exposed to and use alcohol before adulthood but as work, family and other social responsibilities increase during early adulthood most individuals decrease alcohol intake.In dizygotic twins the concordance for alcohol intake decreases during early adulthood while in monozygotic twins it remains stable, which indicates that genetic factors driving alcohol intake become more evident during early adulthood.
-
Alcohol Use is Almost Exclusively Influenced by Social and Familial Factors in Adolescence and Much More Strongly Influenced by Genetic Factors in Early Adulthood
From 1796 members of male-male twin pairs interviewed for their memory of the average number of days alcohol was consumed per month and the average number of consumed per day when drinking. The correlation between monozygotic twins stayed the same over time while the correlation between dizygotic twins while the same as monozygotic twins in adolescence decreased in early adulthood, indicating less of a genetic effect at that time. (Constructed from data in Kendler, K.S. et al. Arch Gen Psychiatry, 65: 674, 2008) ©2010 NBEP
Skip to
CURRENT LESSON OBJECTIVES
- Describe the magnitude of genetic factors in alcohol dependence.
- Identify how both genetic and environmental factors are involved in alcohol use.
- At what age do genetic factors become more evident in alcohol consumption.
- How do adoption studies show that genetics and stress interact in 2 types of alcoholism?
- Why would a biologic factor (endotype) predict alcoholism better than family history?
- What is the most robust genetic factor known to influence the development of alcoholism?
- How do genetic variations in the dopamine D-2 receptor relate to alcohol dependence?
- How does the D2 A1 allele interact with stress, rule setting and treatment?
- How do genetic variations in GABA-A receptors relate to alcoholism?
- How do genetics of the u-opioid receptor relate to effects of alcohol and alcoholism
- How are genetic variations in the CRF system related to alcohol seeking
- How does variation in a glutamate receptor relate to alcohol problems?
- How would changes in endocannibinoid metabolism effect alcohol use
- Why would variations in nicotine receptors relate to alcohol use.
- How would genetic related lower NPY levels relate to stress induced alcohol drinking?
RELATED RESOURCES
Related Clinical Cases
- Adolescent Drinking (Sneaky Teen is Not Squeeky Clean)
- Alcohol Withdrawal focuses on
- Binge Drinking in College (Rebel Without a Cause)
- Fetal Alcohol Syndrome (FAS) focuses on
Related Quizzes
- Alcohol and accidents focuses on
- Alcohol and adolescence focuses on
- Alcohol Genetics focuses on
- Alcohol withdrawal focuses on
- Diagnosis and treatment focuses on
- Epidemiology
- Fetal alcohol syndrome focuses on
- Medical complications
- Neurobiology focuses on
- Pharmacology and acute effects alcohol
- Regular drinking focuses on