Increasing serotonin by intraventricular injection, precursor loading, serotonin releasers, and serotonin uptake inhibitors decreases alcohol intake. Serotonin 3 receptor antagonists block alcohol-stimulated release of dopamine in the mesolimbic dopamine system. The serotonin 3-receptor antagonist ondansetron has shown efficacy in the treatment of individuals with early onset alcohol dependence.
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CURRENT LESSON OBJECTIVES
- What is the role of the GABA system and neurosteroids in alcohol effects and withdrawal?
- How does alcohol interact with the dopamine reward system?
- Describe the effects of alcohol on the opioid system.
- Identify the effects of alcohol on the glutamatergic system.
- Describe the role of corticotrophin-releasing factor (CRF) in alcohol dependence.
- Describe the role of the serotonergic system in alcohol dependence.
- How could smoking increase drinking?
- How could marijuana use lead to increased alcohol use?
RELATED RESOURCES
Related Clinical Cases
- Adolescent Drinking (Sneaky Teen is Not Squeeky Clean)
- Alcohol Withdrawal focuses on
- Binge Drinking in College (Rebel Without a Cause)
- Fetal Alcohol Syndrome (FAS) focuses on
Related Quizzes
- Alcohol and accidents focuses on
- Alcohol and adolescence focuses on
- Alcohol Genetics focuses on
- Alcohol withdrawal focuses on
- Diagnosis and treatment focuses on
- Epidemiology
- Fetal alcohol syndrome focuses on
- Medical complications
- Neurobiology focuses on
- Pharmacology and acute effects alcohol
- Regular drinking focuses on