How does the brain signal for satiety and how is taste/texture involved?

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    • Sensory input from the mouth (taste/texture) is relayed to the same cortical areas of the brain that receive satiety signals from the gut.
      • Limbic processes such as the thalamus then integrate hypothalamic energy control signals, largely under the control of gut hormones such as ghrelin, leptin, insulin, and peptide YY.
      • It is interesting to note, studies have shown the length of time between eating and satiety signal is much longer in obese individuals than in normal weight individuals.
      • Also, obese children and adolescents were significantly less accurate in identifying bitter, savory, and salty tastes than normal weight children.

      References

      1. Thiele TE, Stewart RB, Badia-Elder NE, Geary N, Massi M, Leibowit SF, Hoebel BG, Egli M. Overlapping peptide control of alcohol self-administration and feeding. Alcoholism, clinical and experimental research. 2004; 28(2), 288-294.
      1. Overberg J, Hummel T, Krude H, Wiegand S. Differences in taste sentitivity between obese and non-obese chindren and adolescents. Archives of disease in childhood. 2012; 97(12), 1048-1052.
    Taste
    Taste