Is there cross-sensitization between addictive foods and addictive drugs?

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    • Interestingly, sweet preference has also been shown to correlate with a paternal history of alcoholism.
    • In fact, one study found that having a family history of alcoholism increased the chance that one preferred a 5 times stronger sweet taste.
    • Through this association requires further investigation, the implications of these findings is that the tendency toward addiction may be intrinsic.

    References

    1. Kampov-Polevoy AB, Garbutt JC, Khalitov E. Family history of alcoholism and response to sweets. Alcoholism, clinical and experimental research. 2003; 27(11), 1743-1749.
    1. Avena NM, Hoebel BG. Amphetamine-sensitized rats show sugar-induced hyperactivity (cross-sensitization) and sugar hyperphagia. Pharmacology, biochemistry, and behavior. 2003; 74(3), 635-639.
    1. Avena NM, Hoebel BG. A diet promoting sugar dependency causes behavioral cross-sensitization to a low dose of amphetamine. Neuroscience. 2003; 122(1), 17-20.
    1. Avena NM, Carrillo CA, Needham L, et al. Sugar-dependent rats show enhanced intake of unsweetened ethanol. Alcohol (Fayetteville, NY) 2004; 34(2-3), 203-209.
    Addictive Compounds
    Addictive Compounds
  • Rats can be addicted to food.

    Rat Diving into Jello
    Rat Diving into Jello