There been many studies relating the amount of alcohol consumed to the generation of adverse consequences. The differences in metabolism between men and women results in different definitions of moderate and heavy drinking and there are different medical consequences of number of drinks consumed between men and women. In the figure it can be seen that there is a slight protective effect in women under one drink a day but as women drink over two drinks a day there is an increased relative risk of all cause mortality. In men, the number of drinks consumed produces some protection under 2-3 drinks per day and does not produce increased relative risk of all cause mortality until the number is over three per day.